Ball of Foot Pain

Ball of Foot Pain


Neuroma Surgery Alternative Treatments for Runners

Morton’s neuroma is probably the most common nerve condition that causes foot pain in runners. The pain can become progressive over time as the neuroma gets bigger and becomes more intractable. Some runners wait until the pain in the ball of the foot is excruciating before they seek treatment. This is a mistake. If the neuroma has become enlarged and does not respond to self treatments, home remedies, or non-surgical care under the direction of a physician, neuroma removal surgery may be recommended. Interestingly, surgical removal of the damaged, irritated nerve in the ball the foot is the only place in the human body where doctors routinely recommend excision of a nerve as a first-line treatment. Just because surgical excision is routinely recommended does not mean that surgery is the best treatment for runners. Before you consider surgical excision of neuroma you should understand the surgical risks of neuroma surgery as well as the biomechanical implications that are unique to runners.

Risk of Neuroma Surgery in Runners

Surgery is risky. Pain, bleeding, infection, nerve entrapment and painful scarring are just a few of the commonly mentioned risks of neuroma surgery. In fact, almost every surgical consent form I have ever read actually even mentioned “possibility of death” as a risk. But there are some subtle risks to runners that are not as frequently mentioned.

The stability of your foot is especially important when you are a runner. All runners know this. We spend a great deal of time making decisions about running shoes based on the proportion of cushioning versus stability in the running shoe platform. We all know that the right amount of stability decreases our risk of running related injury and allows us to train harder, and run faster.

In the case of a Morton’s neuroma, the enlarged nerve is near the bottom of the foot between the third and fourth metatarsal bones. The metatarsal bones are all bound together by a connecting ligament called the inter-metatarsal ligament. This ligament stabilizes the ball of the foot and prevents your foot from splaying out like a duck when you stand up and bear weight.

Ball of Foot Pain
Neuroma and pain location on the bottom
of the foot.

One risk unique to foot surgery is that you could end up standing on a painful surgical scar. A painful scar on the bottom of the foot is almost impossible to treat. Scars can never be truly removed. If you run, you would obviously not want a painful scar on the bottom of your foot. For this reason surgical incisions are most often placed on the top of the foot, even to remove a nerve on the bottom of the foot.

But when the foot surgeon goes in from the top of the foot, and makes his way down toward the nerve that is causing your neuroma, the nerve is hidden from view, tucked under the intermetatarsal ligament. In order to access and remove this nerve, it is standard practice to cut through the intermetatarsal ligament with a scalpel knife. The nerve pops upward as soon as the ligament is cut in two. The surgeon can then cut the branches of the nerve to remove the neuroma.

After the nerve has been removed, the skin incision is closed with sutures. But the intermetatarsal ligament is never sewn back together. Because this ligament is a stabilizing structure of your foot, it is possible that cutting the ligament will cause some instability in the ball of the foot. This instability can lead to increased pronation. And again, all runners know that excess pronation can cause biomechanical problems and a predisposition to overtraining injuries.

Custom Orthotics

Custom orthotics are specialized shoe inserts that are built based on a mold of your feet. They are truly custom. They are perfect for you, but would not be particularly useful for anyone else, since they are molded especially for you. Custom orthotics are prescribed by a physician with very specific modifications designed to stabilize your foot and take stress off certain anatomic structures. In the case of a runner with a neuroma, the custom orthotics will stabilize the subtalar joint to control excessive pronation. If designed correctly, motion at the midtarsal joint will be limited by the orthotic and decrease the mechanical irritation of the nerve between the metatarsal bones. In some cases a metatarsal pad might be incorporated into the orthotic to take pressure off of the irritated nerve by better supporting the foot under the metatarsal bones. Custom orthotics are one of the first options that you could consider prior to surgery. Although custom orthotics can be relatively expensive, they are completely non-invasive and (unlike neuroma surgery) orthotics have no significant risk of making your foot worse.

Corticosteroid injections

Morton’s neuroma is caused by mechanical irritation of a nerve. The nerve irritation leads to inflammation. The chronic inflammatory response around the nerve leads to swelling around the nerve, and even within the nerve. Over time the inflammation becomes so significant that the nerve undergoes permanent changes. These changes in the nerve consist of “fibrosis” or scar tissue formation as well as the budding of additional new nerve endings within the neuroma. Those additional nerve endings can send signals back and forth across the synapses which your foot perceives as pain. Obviously it would be best to avoid the late stages of a neuroma where the damage is permanent. The goal of the corticosteroid injection to treat a neuroma is to stop all of the inflammation around the nerve, break up any scar tissue and decrease any excess tissue around the nerve that is compressing or contributing to the continued mechanical irritation of the neuroma. The main advantage of a corticosteroid injection for neuroma is that the pain can subside relatively quickly. This of course can allow you to run again without pain if the injection is effective. The risk of a corticosteroid injection when you are a runner is that corticosteroids can cause weakening of collagen that makes up tendons and ligaments. If you have been incorrectly diagnosed with a neuroma, when actually you have a plantar plate tear or pre-dislocation syndrome, those conditions can actually get much worse because the corticosteroid injection weakens the collagen of the joint supporting structures and they can then rupture or tear completely. In that case, the corticosteroid injection would make you worse, not better.

 Neuroma Steroid Injection
Corticosteroid injected around the neuroma. Steroid returns neuroma to normal size.

Alcohol Sclerosing Injection

If the neuroma has been present for a long period of time and it seems that the only viable treatment is removal of the swollen nerve, there is a type of injection that can treat the problem without surgery. Alcohol sclerosing injections are designed to destroy the nerve, and have the same end result of surgery, without all of the tissue damage, destabilization of the foot and risk that is associated with neuroma surgery. Alcohol sclerosing treatment involves injecting a solution of 4% or 6% alcohol directly into the nerve. The alcohol solution causes the myelin sheath around the nerve to degenerate. This slows conduction of the nerve impulses. Basically the nerve ends up withering away and dying.

This treatment is much less invasive than neuroma surgery. There is no incision. There is a much lower risk of infection. There is no cutting of the intermetatarsal ligament that stabilizes the ball of the foot. This treatment is also considerably less expensive than surgery. Instead of having surgery to remove the nerve, you can simply have a series of 3 to 7 injections that can destroy the nerve and stop the pain without all of the surgical risks and costs. If you are one of the small percentage of patients who do not respond to this treatment, you could still have neuroma surgery later if needed.

Neuroma Surgery Guarantee

I have heard patients ask, “Are there any guarantees with neuroma surgery?” The answer is…Yes! There are two guarantees: 1. You will get a scar. 2. You will get a bill. But that’s it! There is no guarantee you will be running pain-free after neuroma surgery.

Neuroma Alcohol Sclerosing Injection
Alcohol is injected directly into the nerve. Nerve withers and dies after sclerosing injection.

Thoughts for Runners with Neuromas to Consider

If you are a runner, it is actually more important to you than the average person that you choose the best treatment. Surgically removing the nerve is not always the best choice if you want to keep running. But once you have made the choice to have neuroma surgery, you cannot go back. Once you have surgery, the anatomy has been altered and the rules have changed. Once you understand the full implications of neuroma surgery and you have considered all of the other treatment options, surgery may in fact be the right choice for you. But you have to go into surgery with eyes wide open, knowing all of the alternatives, and believing that you have tried everything short of surgery to fix the problem. It is critical that you discuss all of the non-surgical options with your surgeon, before you have neuroma surgery.


Ball of Foot Pain COURSE

Learn how the running expert diagnoses and  treats ball of foot pain.



Question and Answer

What are your two top questions about Ball Foot of Pain that we absolutely NEED to answer in our Ball Foot of Pain course?

1. What treatments, including shoes, can I use to avoid surgery and keep on walking & dancing? (Okay, so, I am not a runner 😉 but I still want to keep moving!)

The treatment that you should use to stay active will depend upon the exact condition that is causing the pain in the ball of the foot. That can differ considerably depend upon whether or not you have a neuroma, plantar plate injury, a stress fracture or osteochondritis. There are many different treatments, both conservative and surgical, those that require prescriptions and those that don’t, that can help each of those different conditions. But the real key before considering treatment is to make sure that you understand exactly what is causing the problem. You have to have the right diagnosis to make sure that you are applying an effective treatment.

2. What treatments work when the plantar plate is involved?

When the plantar plate is injured it is basically a sprain of a small ligament on the bottom of the joint where the toe connect to the foot (the metatarsophalangeal joint). Since the ligament has been strained and sprained it has to heal.
The basic approach for treatment of a plantar plate sprain is as follows:
1. decrease motion at the joint so the ligament doesn’t get stressed any further.
2. stop inflammation so that the ligament can actually heal instead of staying chronically inflamed.
3. protect the ligament from further damage.
The simplest routine to achieve all of these things is to apply ice to the foot and tape the plantar plate. In addition many patients by and Steve shoes to be very helpful. But, many patients have to experiment to find shoes that actually seem to make it better and not worse.


Dr. Christopher Segler is an award-winner researcher, lecturer and sports medicine podiatrist in San Francisco who offers house calls and the most advance treatments of running injuries. He is invited to lecture at medical conferences several times each year to teach other foot and ankle surgeons about running biomechanics and the treatment of complicated running injuries. He is also a runner, triathlete and 14-Time Ironman triathlon finisher. If you have a question about a an injury that is keeping you from running, you can reach him directly at 415-308-0833. You can also learn more about neuroma and other causes of pain at